Antioxidants and depression

[esoteric17]

Interesting study.

<!-- m --><a class="postlink" href="http://pt.wkhealth.com/pt/re/acnp/abstract.00012993-200408000-00003.htm;jsessionid=K2KKvLp2GHHwxlG5Cr3wT9N2P0Vv3JN5Z4CGL2k13YYKvfpWChNr!331639​832!181195628!8091!-1">http://pt.wkhealth.com/pt/re/acnp/abstr ... 28!8091!-1</a><!-- m -->

Quote:Results: Plasma TAOP and individual antioxidant levels were found to be lower in patients with depression than those of controls. On the contrary, the patients had high total plasma peroxide levels. OSI values of the patients were significantly higher than those of controls (P = 0.002), and a significant positive correlation between Hamilton Depression Rating Scale (HDRS) and OSI values was found (r = 0.54, P = 0.01).

Conclusions: The patients with major depression are exposed to oxidative stress, and OSI may be useful to reflect the severity of the disease.

[SGM123]

edc

[esoteric17]

More studies, these specifically discussing curcumin (from turmeric). Note that curcumin has low bioavailability generally, unless administered with piperine (black pepper extract).

Curcumin reverses impaired hippocampal neurogenesis and increases serotonin receptor 1A mRNA and brain-derived neurotrophic factor expression in chronically stressed rats.:
<!-- m --><a class="postlink" href="http://www.ncbi.nlm.nih.gov/pubmed/17617388">http://www.ncbi.nlm.nih.gov/pubmed/17617388</a><!-- m -->

Dietary curcumin counteracts the outcome of traumatic brain injury on oxidative stress, synaptic plasticity, and cognition.:
<!-- m --><a class="postlink" href="http://www.ncbi.nlm.nih.gov/pubmed/16364299">http://www.ncbi.nlm.nih.gov/pubmed/16364299</a><!-- m -->

Neuroprotective and anti-ageing effects of curcumin in aged rat brain regions.:
<!-- m --><a class="postlink" href="http://www.ncbi.nlm.nih.gov/pubmed/16802111">http://www.ncbi.nlm.nih.gov/pubmed/16802111</a><!-- m -->

[admin_phpbb3_import1]

Interesting articles. This curcumin forumlation from Life Extension has gotten good reviews:

http://www.lef.org/Vitamins-Supplements/...cumin.html

While more expensive by weight than others, they claim it is actually the most cost-effective due to its bioavailability.

See here for further discussion:

http://immortalhair.forumandco.com/natur...t-t927.htm

[esoteric17]

admin Wrote:Interesting articles. This curcumin forumlation from Life Extension has gotten good reviews:

http://www.lef.org/Vitamins-Supplements/...cumin.html

While more expensive by weight than others, they claim it is actually the most cost-effective due to its bioavailability.

See here for further discussion:

http://immortalhair.forumandco.com/natur...t-t927.htm

I think LEF is generally overpriced. I really like Vitacost's NSI brand (no I don't work for or get any money from Vitacost; I just think they have awesome products at great prices). This one has the black pepper extract in it.

<!-- m --><a class="postlink" href="http://www.vitacost.com/NSI-Turmeric-Extract-Curcumin-C3-Complex-with-Bioperine">http://www.vitacost.com/NSI-Turmeric-Ex ... -Bioperine</a><!-- m -->